| MEDI | Wednesday, August 22, 2007 | ||
1:30 PM-5:00 PM BCEC -- 213, Oral | |||
Phosphodiesterase Inhibitors | |||
| Organizer: | Nick Terrett | ||
| 1:30 PM | 261 | Overview of the biology of the PDE family Eric Karran | |
| 2:00 PM | 262 | Development of PDE4 inhibitors for CNS indications Allen T. Hopper | |
| 2:30 PM | 263 | Discovery of selective PDE7 and PDE7 and 4 dual inhibitors and their role in T cell activation William J. Pitts | |
| 3:00 PM | 264 | Inhibition of the striatal phosphodiesterase PDE10A: Biochemical, behavioral and pharmacological predictors of antipsychotic potential Christopher J Schmidt | |
| 3:30 PM | 265 | Scaffold-based discovery of selective PDE4 inhibitors Kam Y. J. Zhang, Graeme L. Card, Jinyu Liu, Landy Blasdel, Bruce P. England, Chao Zhang, Yoshihisa Suzuki, Sam Gillette, Byunghun Lee, Daniel Fong, Ben Powell, Davin Hsieh, Joshua Neiman, Michael V. Milburn, Brian L. West, Prabha N. Ibrahim, Dean R. Artis, Gideon Bollag | |
| 4:00 PM | 266 | Structure based design of second generation long-acting PDE5 inhibitors Michael J Palmer, Andrew S. Bell, David N. A. Fox, David G Brown | |
| 4:30 PM | 267 | The development of PDE4 inhibitors with improved therapeutic index for the treatment of COPD and asthma Neil J. Press, Clive McCarthy, Roger Taylor, Rene Hersperger, Thomas Keller, Joe Fullerton, Nicola Arnold, Lyndon Brown, Julia Hatto, Mark Mercer, Helen Oakman, Cathy Ritchie, Peter Gedeck, Martin Gosling, Andrea Hankin, Denise Head, Alexandra Smith, Rowan Stringer, Brian Everatt, Louise Dalrymple, Janet Maas, Elisabeth Schaeublin, Keith Butler, John R. Fozard, Lazzaro Mazzoni, Nicolaou Beckmann, Frederic Bernard, Olivier Bonneau, David Farr, Deborah Hynx, Morris Tweed, Daniel Wyss, Thomas Buhl, Moise Azria, Beate Vogel, Alexandre Trifilieff | |
Symposium Grid -- Division of Medicinal Chemistry -- Session Listing
The 234th ACS National Meeting, Boston, MA, August 19-23, 2007