BIOTTuesday, August 21, 2007

3:00 PM-5:25 PM BCEC -- 107A, Oral
Upstream Processing: Advances in Cell Culture Process Development
Organizers:Susan T. Sharfstein
Ilse Blumentals
Gargi Maheshwari
3:00 PMIntroductory Remarks
3:05 PMLeveraging process characterization and validation data for continuous process improvement
Minh Luu, Robert Kiss, Steven Meier
3:25 PMInhibitory threshold values of lactate, ammonia, carbon dioxide, and osmolality in CHO cell culture for a therapeutic protein production
Zizhuo Xing, Zhengjian Li, Vincent Chow, Steven S. Lee
3:45 PMScale-up of mammalian cell cultures controlled by automated flow cytometry
Greg Sitton, F. Srienc
4:05 PMIntermission
4:20 PMMetabolic process engineering applied to cell culture production processes
Bernhard M. Schilling, Abhinav A. Shukla, Steven Lee
4:40 PMInvestigating limitations during process development at reduced perfusion rates
Hans Drouin, Stéphane Lanthier, Amine Kamen, James M. Piret, Yves Durocher
5:00 PMHigh-throughput cell culture process development using 3-D microbioreactors and online quantifications of cell growth and GFP expression
Xudong Zhang, Yuan Wen, Shang-tian Yang
5:20 PMConcluding Remarks

Upstream Processing: Advances in Cell Culture Process Development -- Next Session

Symposium Grid -- Division of Biochemical Technology -- Session Listing

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007