| BIOT | Sunday, August 19, 2007 | ||
8:00 AM-11:10 AM BCEC -- 107 A/B, Oral | |||
Biophysical and Biomolecular Symposium: Protein Stability | |||
| Organizers: | Erik J. Fernandez Nitin Rathore C. Russell Middaugh Angela Blake-Haskins Angela Blake-Haskins | ||
| 8:00 AM | Introductory Remarks | ||
| 8:05 AM | 8 | Use of biophysical techniques for manufacturability assessment of therapeutic proteins Cynthia Li, Yijia Jiang, Juraj Svitel, Jie Wen, Ranjini Ramachander, Shengwu Wang, Jenny Li, Linda Narhi | |
| 8:25 AM | 9 | A novel bioseparation approach: Use of chaotropic agents for HIC and ion exchange chromatography to dissociate noncovalent multimers during purification of an Fc fusion protein Allen B. Magill II | |
| 8:45 AM | 10 | Aggregation of a monoclonal antibody induced by adsorption to microparticle surfaces Jared Bee, Jennifer Stevenson, Koustuv Chatterjee, Erwin Freund, John F. Carpenter, Theodore W. Randolph | |
| 9:05 AM | 11 | Assessment of protein stability during freeze-thaw process Kapil Gupta, Nitin Rathore, Lorena Barron, Wenchang Ji, Feroz Jameel, Keith Murphy | |
| 9:25 AM | Intermission | ||
| 9:45 AM | 12 | Identifying optimal solution conditions for high concentration protein formulations: Use of self-interaction chromatography Mark Cornell Manning, Charles S. Henry, Joseph J. Valente, Robert W. Payne, W. William Wilson | |
| 10:05 AM | 13 | Stability of high concentration rhuMAb VEGF Hong Liu, Mary E. M. Cromwell | |
| 10:25 AM | 14 | Stability of protein antigens in vaccine delivery formulations James D Chesko, Jina Kazzaz, Padma Malyala, Kathryn Patton, Mildred Ugozzoli, Derek O'Hagan, Manmohan Singh | |
| 10:45 AM | 15 | Tungsten, prefilled syringes and protein aggregation Robert Swift, Yasser Nashed-Samuel, Wei Liu, Linda Narhi, Janice Davis | |
| 11:05 AM | Concluding Remarks | ||
Symposium Grid -- Division of Biochemical Technology -- Session Listing
The 234th ACS National Meeting, Boston, MA, August 19-23, 2007