CHED 202 |
| The periplasm of the bacterial cell wall contains the peptidoglycan layer. Peptidoglycan is a mesh of cross-linked sugars and peptides that is responsible for maintaining cell shape and integrity. The peptidoglycan is synthesized by bifunctional enzymes with transglycosylase and transpeptidase activity known as penicillin-binding proteins (PBPs). We will describe the cloning and overexpression of a putative PBP from Burkholderia cenocepacia. The genome for this strain,J2315, has been sequenced at the Sanger Institute. The open reading frame identified as BCAM 2632 has been identified as a gene homologous to PBP1a from E.coli. Studies characterizing the BCAM 2632 gene product will be described.
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Undergraduate Research Poster Session
2:30 PM-4:30 PM, Monday, August 20, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Chemical Education |