WCC 7 |
| A structure-property approach toward the synthesis of novel biomaterials was investigated. The new materials include polyester-based elastomers with similar mechanical properties to ligaments and vascular structures, as well as cyclic diacid-based amine-functionalized polymers. These materials possess a unique combination of features. Specifically, they are liquid at room temperature, readily crosslinked and processed, biocompatible, biodegradable and functionalized. Amine-functionalized poly(butadiene) materials were also prepared and evaluated for their effectiveness as gene delivery vectors. The cytotoxicity, polyplex formation and transfection efficiency were determined and structure-property relationships established. More recently, these studies were extended to include polyurethane elastomers. The polyurethane synthesis incorporates hydroxy endcapped polyesters and amine-functionalized poly(butadiene)s to alter polymer properties. The design, synthesis, properties and processing of these materials will be discussed. |
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Many Faces of Chemistry: Women at the Forefront
1:30 PM-4:20 PM, Monday, August 20, 2007 Westin Boston Waterfront -- Revere, Oral
Women Chemists Committee |