ANYL 129 |
| A sensitive electrochemical immunoassay method for carcinoembryonic antigen (CEA) detection using CdS nanocrystal tracers and multi-wall carbon nanotube-polyallylamine modified screen printed electrode (MWCNT-PAH/SPE) was described. The sandwich immunoassay was performed with anti-CEA antibody immobilized on MWCNT-PAH/SPE and CEA followed by cadmium sulfide nanocrystal labeled anti-CEA antibody (αCEA-CdSNC). The square wave anodic stripping voltammetry (SWASV) was used to get amplified signal current response obtained from the dissolved αCEA-CdSNC. The calibration curve for CEA concentration in the range of 0.005 - 100 ng mL-1 and a detection limit of 3 pg mL-1 (S/N = 3). The high precision and sensitivity of this method provides a feasible means of determining urinary CEA, which is more useful than serum CEA in the early detection of urotherlial carcinoma. |
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General Posters
7:00 PM-9:00 PM, Sunday, August 19, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Analytical Chemistry |