NMR and AFM investigation of supramolecular nanostructures

ANYL 461

Minghui Chai, minghui.chai@cmich.edu1, Keith Freel, freel1k@cmich.edu1, Aaron K. Holly1, Casey Manning1, Luvena Ong2, Peijie Ong2, Ravi Srinivas1, Martin F. Federle, minghui.chai@cmich.edu1, and Ewa K. Groski, minghui.chai@cmich.edu1. (1) Department of Chemistry, Central Michigan University, Mt. Pleasant, MI 48859, (2) Mt. Pleasant High School
In this study, NMR spectroscopy has been utilized to investigate the supramolecular nanostructures including host-guest complexes and self-assemblies. Materials with nanoscale pores such as dendrimers and cyclodextrins were used as the hosts for the complexes, or templeates for the self-assemblies; and the guests studied included pharmaceutical drugs, amino acids and fatty acids. Atomic force microscopy (AFM) was used to probe the dendrimer based self-assemblies, which provides the information on the sizes and interactions of the system by vivid AFM topographic images and force distance curves.