An NMR spectroscopic study of reaction of 1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane with ammonium fluoride

ANYL 66

Martin E. Nunez, nfrasser@yahoo.com, Augusto Rivera, ariverau@unal.edu.co, Eliseo Avella, eavellamo@unal.edu.co, and Jaime Rios, jariosmo@unal.edu.co. Departmento de Química, Universidad Nacional de Colombia, Bogota, Colombia
Reactions of 1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane with ammonium fluoride to yield 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane at 20 ºC were investigated using NMR to follow the concentration of reactant and product with the time to address the mechanism of substitution.

Besides, by doing experiment 1D COSY and TOCSY to the mixture of reaction was found that 1,3,5-triazabicyclo[3.2.1]octane and 2-(1,3,5-triazabicyclo[3.2.1]oct-3-yl)ethanamine are compounds participating in the conversion.

 

General Posters
7:00 PM-9:00 PM, Sunday, August 19, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Analytical Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007