INOR 766 |
| The dynamics of surface recognition and binding at the protein interface is a key component of intermolecular electron transfer (ET) reactions. This study probes how anionic gold nanoparticles enhance the ET reactivity of cytochrome c. Stopped-flow UV-Vis spectroscopy monitors the reaction of the protein-nanoparticle adduct with small redox reagents. The ET rate is affected by the surface properties of the nanoparticle, including charge, hydrophobicity, and the substituents. The rate constants are significantly attenuated by charge screening, suggesting that the nanoparticle promotes reactivity through preassembly of the reagents. |
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Bioinorganic Chemistry: Enzymes and Coenzymes
7:00 PM-10:00 PM, Tuesday, August 21, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Inorganic Chemistry |