Synthesis and properties of repeating sequence copolymers of PLGA

POLY 256

Ryan M. Stayshich, rms34@pitt.edu, Jian Li, and Tara Y. Meyer, tmeyer@pitt.edu. Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260
PLA and PLGA are two of the most important biodegradable and biocompatible polymers made derived from renewable plant resources. These polymers can be tuned for particular applications by controlling the microstructure, both the sequence and stereochemistry. In order to better correlate the properties with microstructure, a series of dimeric and trimeric units of lactic and glycolic acid have been prepared and polymerized using condensation methods. The properties of these polymers including phase behavior, hydrolysis rates and mechanical properties have been measured and interpreted as a function of sequence.
 

Polymers from Renewable Resources
8:20 AM-11:45 AM, Monday, August 20, 2007 Westin Boston Waterfront -- Douglas, Oral

Division of Polymer Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007