POLY 295 |
| Professor Robert Langer, who first established the feasibility and practicality of sustained drug delivery from polymers, has provided guidance to local drug delivery programs with which I have been involved for some fourteen years. First, as a Scientific Founder and Board Member of Focal, Inc, his expertise facilitated our ability to deliver many types of therapeutics, ranging from insoluble small molecules to proteins, even to genes. Our delivery platform was based on synthetic, adherent poly(oxyethylene)-based hydrogels. Subsequently, as a consultant to Genzyme Corporation, he has provided important insights into sustained drug delivery from our hyaluronan (HA)-based hydrogels. HA, which is ubiquitous in the body, can bind to a variety of cell and matrix receptors and can be modified with bioactives at its carboxyl and hydroxyl functions for specific cell targeting. Our work on the combination products indicated above has resulted in promising approaches to treatment of a variety of localized conditions. |
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Herman Mark Award in Honor of Robert Langer
1:00 PM-4:55 PM, Monday, August 20, 2007 Westin Boston Waterfront -- Grand Ballroom B, Oral
Division of Polymer Chemistry |