Anion recognition and activation by heterocyclophane and tripodal polyammonium receptors

INOR 338

Enrique García-España, enrique.garcia-es@uv.es1, M. Teresa Albelda, teresa.albelda@uv.es2, Salvador Blasco2, Raquel Belda, salvador.blasco@uv.es2, M. Alejandra Sornosa-Ten, alejandra.sornosa@uv.es2, M. Paz Clares, m.paz.clares@uv.es2, Jorge González2, José Miguel Llinares, jollibe@uv.es2, Conxa Soriano, concepcion.soriano@uv.es2, Estefanía Delgado-Pinar2, Juan Carlos Frías, juan.frias@uv.es2, and Javier Alarcón, javier.alarcon@uv.es3. (1) Institute of Molecular Science, University of Valencia, C/ Dr. Moliner 50, Burjassot, 46100, Spain, (2) Institute of Molecular Sciences, University of Valencia, Apdo Correos 22085, Valencia, 46071, Spain, (3) Department of Inorganic Chemistry, University of Valencia, C/ Dr. Moliner 50, Burjassot (Valencia), 46100, Spain
Polyamine compounds are ambivalent ligands able to coordinate metal ions or anions depending on the pH of the medium. When the pH is low enough the positively charged ammonium groups can interact with oppositely charged species through electrostatic interactions. At sufficiently high pH values, polyamines interact with metal ions through the electron pairs of their amino groups forming coordinative bonds. These coordination modes can be modulated by the presence of aromatic fragments within the molecule. For instance, with respect to anion coordination, aromatic moieties provide hydrophobic environments in which electrostatic interactions are reinforced. If the anions have also aromatic components they can give rise to stacking interactions. With respect to metal ions, the aromatic fragments can serve as spacers organizing the coordination sites of the molecule. Aromatic components can yield pi-cation interactions and, if they contain heteroatoms, can contribute to the binding through coordinative bonds. Additionally, appropriate aromatic fragments can aid in the recognition of metal ions and anions through the appearance or modification of a physical signal such as the fluorescence emission. Some recent results concerning polyamine receptors of either open-chain, tripodal or cyclic nature will be presented. Attention will be paid to the metal ion and anion coordination behaviour of these compounds and the possibility they have to act as chemosensors. As a final point the incorporation of the polyamines in different solid supports will be discussed.