Small plant with big ambitions: Triterpene biosynthesis in arabidopsis

BIOL 84

Mariya D. Kolesnikova, mdk@rice.edu1, David A. Lynch2, Allie C. Obermeyer1, Quanbo Xiong2, William K. Wilson2, and Seiichi P. T. Matsuda, matsuda@rice.edu3. (1) Chemistry, Rice University, 6100 Main str, MS-60, Houston, TX 77005, (2) Department of Biochemistry and Cell Biology, Rice University, 6100 Main str, MS-140, Houston, TX 77005, (3) Department of Chemistry and Department of Biochemistry and Cell Biology, Rice University, 6100 S. Main St. MS 65, Houston, TX 77005
Arabidopsis thaliana is a small model plant, and its genome has been completely sequences. Thirteen oxidosqualene cyclases have been identified in Arabidopsis. We present characterization of several oxidosqualene cyclases, which can make at least a third part of known triterpene skeletons. The variety of triterpene structures, mechanisms of their formation and phylogenetic relationships will be presented.