ANYL 458 |
| Fibrous scaffolds of hydroxyethyl cellulose (HEC) were produced using electrospinning technique by blending it with poly (vinyl alcohol) (PVA). Different ratio of HEC : PVA (50:50, 60:40 and 70:30) composite fibers were prepared. Electrospun mats of HEC : PVA (50:50) were used for this study. The microstructure of the obtained nanofibers were analyzed by scanning electron microscopy (SEM) and the mechanical properties of the blend nanofibrous mats were examined by tensile test. The weight ratio of HEC / PVA in blends greatly influenced the mechanical properties of the blend nanofibrous mats. Human brain cancer cell (U251) proliferation and morphology on these nanofibers were studied. Cellular assays showed excellent cell attachment and proliferation. The cell morphology and cell-matrix interaction were studied using SEM and fluorescence actin staining images. The cell viability is slightly higher for these blend nanofibrous mats compared to pure PVA nanofibers. |
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Analytical Approaches
1:30 PM-4:30 PM, Thursday, August 23, 2007 BCEC -- 104C, Oral
Division of Analytical Chemistry |