POLY 131 |
| The development of hybrid organic/inorganic particles as chromatographic packing materials has been a great advance for reversed-phase HPLC. Hybrid particles allow for similar selectivity and method development and have increased chemical stability toward alkaline mobile phases when compared with traditional silica-based packing materials. Since initial commercialization of methyl hybrid columns in 1999, our group has continued to research the synthesis of hybrid particles and evaluate the use of these materials in chromatographic applications. This report will cover the synthesis of hybrid particles based on different molar ratios of organofunctional silanes. In particular we will explore mixed condensation reactions of tetraethoxysilane with 1,2-bis(triethoxysilyl)ethane. Attention is focused on developing methods to prepare highly spherical particles with desirable pore properties.
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General Papers: Functional Materials
6:00 PM-8:00 PM, Sunday, August 19, 2007 BCEC -- Exhibit Hall - B2, Poster
Sci-Mix
Division of Polymer Chemistry |
