Atomic force microscope observation on friction of phospholipid micro domains in monolayer

COLL 236

Takakuni Oguchi, j7206617@ed.noda.tus.ac.jp1, Kazuhiro Matsuda1, Takahiro Ohkubo2, Kenichi Sakai1, Hideki Sakai2, and Masahiko Abe2. (1) Faculity of Science and Technoligy, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan, (2) Faculty of Science and Technology, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan
Friction of dilauroylphosphatidylcholine (DLPC) / distearoylphosphatidylcholine (DSPC) micro domains in monolayer has been studied with atomic force microscope (AFM). The lipid film was prepared via the Langmuir-Blodgett (LB) technique on mica. The friction of DSPC-rich domains was measured to be larger than that of DLPC-rich ones at 25¢ªC. The increase in temperature to 80¢ªC results in a decrease in the friction of DSPC-rich domains, whereas any significant difference was not observed for the DLPC-rich domains. The observed decrease in the friction of DSPC-rich domains may result from the phase transition, i.e. from gel to liquid crystal phases. We focus on an effect of immersion to water of the DLPC/DSPC monolayer formed on mica, on the basis of the surface morphology data monitored with AFM.
 

Fundamental Research in Colloid and Surface Chemistry
6:00 PM-8:00 PM, Monday, August 20, 2007 BCEC -- East Registration, Poster

Division of Colloid & Surface Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007