ANYL 341 |
| Coherent anti-Stokes Raman scattering (CARS) microscopy has experienced a recent renewal of interest due to its promise of providing detailed chemical information based on endogenous contrast. We present an interferometric time-domain Fourier transform implementation of coherent anti-Stokes Raman scattering (FTCARS). The method gives high resolution CARS spectra over the large bandwidth of a single femtosecond laser source (1500 cm-1), providing the ability to image multiple vibrational modes simultaneously. FTCARS employs a collinear geometry, and allows for straight-forward removal of the non-resonant background. We discuss recent progress towards improving the sensitivity of FTCARS microscopy for biological applications. |
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Biological Applications of Nonlinear Optics
8:30 AM-12:10 PM, Tuesday, August 21, 2007 BCEC -- 104A, Oral
Division of Analytical Chemistry |