Quantitative determination of fullerenes in combustion by-products and during toxicological assays

ENVR 54

Carl W. Isaacson, isaacsoc@onid.orst.edu1, Crystal Usenko2, Robert Tanguay2, and Jennifer A. Field, jennifer.field@orst.edu2. (1) Department of Chemistry, Oregon State University, Gilbert Hall, Corvallis, OR 97331, (2) Environmental and Molecular Toxicology, Oregon State University, 30 Campus Way, ALS II, Corvallis, OR 97331
The increasing production of fullerenes and carbon-based nanomaterials has led many researchers to study the potential of these materials to impact human and environmental health. This research is hampered by the lack of quantitative analytical methods for the analysis of fullerenes and carbon-based nanomaterials. The research present herein, demonstrates a quantitative method based on liquid-liquid extraction or pressurized liquid extraction followed by LC-MS for a suite of fullerenes. The method was applied during the course of a toxicological assay of embryonic zebrafish to determine the up-take of a model nanomaterial, C60, by the zebrafish and the sorption of C60 to the vial from solution. The method was also applied to determine the concentration of fullerenes in soot samples collected from residences with wood burning stoves.
 

Symposium Honoring Dr. Walter Giger
1:30 PM-5:15 PM, Monday, August 20, 2007 Boston Park Plaza -- Stanbro Rm, Oral

Division of Environmental Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007