PHYS 307 |
| A key goal for bottom-up nanofabrication methods such as self-assembly has been to generate structures whose complexity matches that achieved by top-down methods. I describe a method for folding long single strands of DNA into arbitrary two dimensional target shapes. Self-assembled in a one-pot reaction from the 7 kilobase genome of phage M13mp18 and more than 200 synthetic oligodeoxynucleotides, the shapes are roughly 100 nanometers in diameter and nearly 5 megadaltons in mass. Experimental shapes approximate target shapes, such as a 5-pointed star, with a resolution of 6 nanometers and may be decorated by patterns at the same 6 nanometer resolution to form words or images. These structures may be thought of as a versatile "nanobreadboard", a simple platform for creating arbitrary nanostructures such as nanocircuits. |
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Emergence of Function in Molecular Assemblies
1:20 PM-5:00 PM, Wednesday, August 22, 2007 BCEC -- 157B, Oral
Division of Physical Chemistry |