Using "click" chemistry to tether ligands to gold nanoparticles

COLL 170

Michael W. Heaven, mheaven@email.unc.edu, Christopher A. Beasley, chris-beasley@unc.edu, and Royce W. Murray, rwm@email.unc.edu. Department of Chemistry, The University of North Carolina at Chapel Hill, Kenan Laboratories of Chemistry, Kenan C345, Chapel Hill, NC 27599-3290
Gold nanoparticles with diameter of less than 2 nanometres are generally stabilized from aggregation by a monolayer of ligand. These gold monolayer protected clusters (MPCs) can than undergo ligand exchange with other ligands of interest with more dynamic functionality. Our aim has been to design, through the cycloadditon of azide and terminal alkyl ligands, linkages between MPCs and well known redox active and fluorescent moieties. This allows us to examine and contrast how the interaction of MPCs and the ligands differ when tethered rather than as separate entities.
 

Fundamental Research in Colloid and Surface Chemistry
6:00 PM-8:00 PM, Monday, August 20, 2007 BCEC -- East Registration, Poster

Division of Colloid & Surface Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007