Synthesis of amphiphilic ABA triblock copolymer with well-defined glycopolymer segments via ATRP

POLY 171

You-Yi Xu, opl-yyxu@zju.edu.cn, Jian-Yu Wang, Yan-Ling Qian, Fan Zhang, and Bao-Ku Zhu. Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China
A novel amphiphilic ABA triblock copolymer with well-defined glycopolymer segments was synthesized by the atom transfer radical polymerization (ATRP) using a bromo-terminated difunctional polysulfone as macroinitiator. The macroinitiator was prepared by esterifying the phenolic end groups of polysulfone to á-haloesters. This macroinitiator was then used to initiate the polymerization of a sugar-carrying methacrylate monomer, 3-O-methacryloyl-1,2:5,6-di-O-isopropylidene-D-glucofuranose, resulting a triblock glycopolymer. After acidolysis treatment, the isopropylidenyl groups of the protected sugar residues were removed, thus the amphiphilic ABA triblock copolymer with well-defined glycopolymer segments was obtained.