Enantioselective carcinogenesis of agrochemicals and other xenobiotics

AGRO 125

Imran Ali, drimran_ali@yahoo.com, Department of Chemistry, Jamia Millia Islamia (Central University), Jamia Nagar, -, New Delhi, 110025, India
Generally, one of the enantiomers of racemic agrochemicals is carcinogenic/toxic than its antipode. Therefore, the data available on the carcinogenesis of the racemic mixtures of the chiral pollutants is not reliable and need modification in terms of the enantioselective carcinogenesis. It is essential to explore the enantioselective carcinogenesis due to different toxicities of the chiral pollutants. The knowledge of the stereoselective metabolisms of the chiral pollutants may be useful for cancer treatment. The enantioselective carcinogens/toxicities due to chiral pesticides, polynuclear aromatic hydrocarbons and other xenobiotics have been discussed.