INOR 312 |
| Nitric oxide (NO) is a regulatory molecule that controls various biological functions such as vasodilation, neurotransmission, and immune response. There has been much interest in the development of compounds for the controlled delivery of NO to biological targets on demand. Metal nitrosyls represent a promising class of new NO donors due to their ability to release NO upon illumination with light. While there has been much exploration into the photodissociation of NO from ruthenium and iron nitrosyls, to date, only one manganese nitrosyl exhibits this type of reactivity. In an effort to gain insight into this unique chemical behavior, we have employed various pentadentate ligands to isolate new diamagnetic {Mn-NO}6 nitrosyls. The syntheses, structures, and the characteristics of photodissociation of NO of these manganese nitrosyls will be reported. The principles of tuning the photoactivation process will also be emphasized. |
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Synthetic Coordination Chemistry
7:00 PM-10:00 PM, Sunday, August 19, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Inorganic Chemistry |