Photophysics of platinum(II) polypyridines: Effects of DNA binding and carbometalation

INOR 144

Meaghan L. Clark, clark13@purdue.edu1, David R. McMillin, mcmillin@purdue.edu1, Stéphane Diring2, and Raymond Ziessel2. (1) Department of Chemistry, Purdue University, 560 Oval Drive, Box 352, West Lafayette, IN 47907, (2) Ecole de Chimie, Laboratoire de Chimie Moléculaire, Polymères et Materiaux, ULP, 25 rue Becquerel, 67087, Strasbourg, Cedex 02, France
Platinum(II) polypyridines have proven useful for biological and chemical sensing and as luminescent labels. Platinum(II) compounds are typically not emissive at room temperature due to deactivation via low-lying 3d-d states. However, the substituents on the 3' or 4' position of the polypyridine ligand, the co-ligand, and/or carbometalation can give rise to long lived photoluminescence. In this work the DNA binding and photophysical properties of Pt(4'-X-trpy)CN+ compounds where 4'-X-trpy denotes 4'-dimethylamino-2,2':6'2”-terpyridine (dma-T) or 4'-pyrrolidinyl-2,2':6',2”-terpyridine (pyrr-T) were studied. We have also looked at several carbometalated systems with acetylide co-ligands.
 

Bioinorganic Chemistry: DNA and RNA
1:30 PM-5:30 PM, Sunday, August 19, 2007 BCEC -- 211, Oral

Division of Inorganic Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007