Mosquito repellency of Amyris and Siam-wood essential oils

AGRO 39

Gretchen E. Paluch, gre@iastate.edu and Joel R. Coats, jcoats@iastate.edu. Department of Entomology, Iowa State University, 112 Insectary, Ames, IA 50011
In recent years there have been efforts to develop new mosquito repellents. Previous studies in our laboratory on the repellent properties of essential oils have identified mixtures of natural products that yield residual repellency effects (both spatial and contact). Mixtures that include monoterpenes (provide good spatial repellency) and oxygenated sesquiterpenes (provide good contact repellency) result in good efficacy via both modes of action. Amyris (Amyris balsamifera) and Siam-wood (Fokeina hodginsii) essential oils contain large amounts of sesquiterpene alcohols including elemol, valerianol, and isomers of eudesmol. These individual components were isolated out of the parent essential oils and evaluated for mosquito-repellent activity in laboratory bioassays. Studies on the structure-activity relationships are currently underway to explain differences in the repellent effects observed in the bioassays. The results of this study will contribute to our understanding of the bioactivity of plant-derived sesquiterpenoids and provide insight for mechanistic studies on naturally-occurring repellent compounds.