Controlled functionalization and quantification of organic molecules on mesoporous silica nanoparticles

CHED 278

Rose E. Kohl, rkohl@iastate.edu1, Brian G. Trewyn, bgtrewyn@iastate.edu2, and Victor S-Y. Lin, vsylin@iastate.edu2. (1) Department of Chemistry, Iowa State University, 2702 Gilman Hall, Ames, IA 50011, (2) Department of Chemistry and Ames Laboratory, Iowa State University, 1605 Gilman Hall, Iowa State University, Ames, IA 50011
With the new advances in biological and catalytic applications with mesoporous silica nanoparticles (MSNs), there has come a need for functionalizing the surfaces with organic and inorganic species - not only a need to functionalize, but to selectively functionalize the interior pore surfaces differently than the external particle surface. We have investigated, through controlled reaction conditions, that the different surfaces (exterior and interior) can be functionalized with organic molecules by incorporating both the co-condensation and post-synthesis grafting method. We also will be quantifying the degree of functionalization using published methods. The MSN is fully characterized using electron microscopy, nitrogen sorption, X-ray diffraction, and FTIR. Following synthesis, characterization, and quantification, we will investigate the particle interaction with living biological systems.
 

Undergraduate Research Poster Session
2:30 PM-4:30 PM, Monday, August 20, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Chemical Education

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007