PROF 11 |
| As an academic medicinal chemistry laboratory in a school of pharmacy, we are interested in exploring new approaches to improve the therapeutic effectiveness and decrease the systemic toxicity of cancer chemotherapy. Our main research interests are to design, synthesize, and evaluate new prodrug systems for the site-specific delivery and activation of anticancer drugs in tumor tissues and to discover new anticancer agents with novel mechanisms of action. This presentation will highlight our research projects exploring nitroreduction and proteolysis as trigger mechanisms for the site-specific activation and delivery of anticancer drugs to tumor tissues, and the design and discovery of small molecule inhibitors of protein-protein interactions involved in angiogenesis and oxidative stress. |
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Progress of Chinese-Americans in Academia
1:00 PM-4:45 PM, Sunday, August 19, 2007 Sheraton Boston -- Back Bay Blrm C, Oral
Division of Professional Relations |