AGRO 72 |
| Beauvericin (BEA) is a cyclic hexadepsipeptide mycotoxin, which has been found in the secondary metabolites of Beauveria bassiana, Paecilomyces fumosoroseus, Paecilomyces tenuipes, Polyporus sulphurous, and a variety of Fusarium species. BEA shows antimicrobial, insecticidal, cytotoxic, and apoptotic activity, which means it can be developed and used as bioinsecticide and human medicine. However, BEA production of the microorganisms is limited and the fermentation technology is not preferable at present. The concentration of BEA obtained from the culture of Fusarium sp. is only 5 mg/g mycelia. In this study an endophytic fungus Fusarium sp. F-1, which was isolated from a seagrass Spartina alterniflora, was investigated to improve BEA yield and to shorten production time by using a dynamic fermentation with a low aeration condition instead of a usual static fermentation. Thin layer chromatography and high performance liquid chromatography were applied to analyze BEA in the cultures. The results indicated that the aeration condition might be the key. |
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New Developments and Issues in Agrochemical Sciences
8:00 AM-11:00 AM, Monday, August 20, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Agrochemicals |