Preparation of 3-D aerogel protein array

BIOL 233

Jui-Chuang Wu, ray_j_wu@cycu.edu.tw, R&D Center for Membrane Technology and Department of Chemical Engineering, Chung Yuan Christian University, Taiwan, ROC, 200, Chung Pei Rd, Chung Li, Taoyuan County, 32023, Taiwan
Three-dimensional biochips prepared in this study are composed with a glass slide and aerogel dots on it. The aerogel was produced by the sol-gel process using an ionic liquid as the template followed by an solvent extraction to remove the template and build a three-dimensional mesoporous structure. The aerogel dots on chips were chemically modified and further verified their functionality as biochips by performing a sandwich immunoassay on the top of the aerogel dots. The signal intensities were observed to amplify in around two magnitudes of order due to the enormous surface area generated by the aerogel compared with those on two-dimensional flat glass surfaces.
 

Frontiers in Chemical Biology
5:00 PM-7:00 PM, Wednesday, August 22, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Biological Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007