COLL 192 |
| The self-assembly of bio-conjugated colloidal nanomaterials has versatile technological potential for the development of novel micro and nanostructures, molecular machines, and biosensing devices. Here we report the synthesis of gold nanoparticles directly conjugated to lipid molecules and the formation of a self-assembled monolayer of nanostructures. The nanoparticles were prepared by a phase transfer method, which involved the reduction of potassium tetrachloroaurate(III) by sodium citrate in an aqueous solution and the simultaneous transfer of the reduced species to an organic medium containing DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine). The resulting nanoparticles were characterized using Uv-vis spectroscopy and dynamic light scattering particle-size analysis. The diameters of the nanoparticles ranged from 25 to 30 nm. The Langmuir-Blodgett technique was utilized to allow the self-assembly of DMPC-capped nanoparticles onto a water subphase at room temperature, and the formation of a monolayer was monitored by the measurement of the compression isotherm. This method of synthesis of ordered structures utilizing biomolecular interactions would be useful in manufacturing novel metamaterials and nanocircuits. |
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Fundamental Research in Colloid and Surface Chemistry
6:00 PM-8:00 PM, Monday, August 20, 2007 BCEC -- East Registration, Poster
Division of Colloid & Surface Chemistry |