Surface imprinted silica nanoparticles for FRET based detection of methyl salicylate

COLL 208

Clint B Smith, clint.b.smith@erdc.usace.army.mil1, John E Anderson1, and Balaji Tatineni, btatineni@vcu.edu2. (1) US Army ERDC, 7701 Telegraph Road, Alexandria, VA 22315, (2) Dept. of Chemistry, Virginia Commonwelath University, 1001 West Main Street, Rchmond, VA 23284
Fluorescence resonance energy transfer (FRET) is a process in which energy is transferred non-radiatively from a donor in an excited electron state to an acceptor fluorophore. FRET is distinctive in its ability to reveal the presence of specific recognition of select targets such as the nerve agent stimulant Methyl Salicylate (MES) upon spectroscopic excitation. The acceptor, MCM-41 nanoparticles, were surface imprinted with the donor, MES, which demonstrated an energy transfer and stokes shift of 130 nm with a 320 nm excitation and a 550 nm emission at pH 9. The molecularly imprinted silica nanoparticles were synthesized using methyl salicylate (MES), Terbium (Tb), Tetraethyl orthosilicate (TEOS) as a precursor, Tetrabutylammonium hydroxide (TBAOH), and cetyltrimethylammonium bromide (CTAB), as a template.
 

Fundamental Research in Colloid and Surface Chemistry
6:00 PM-8:00 PM, Monday, August 20, 2007 BCEC -- East Registration, Poster

Division of Colloid & Surface Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007