Synthesis and photolysis of dendron based phototrigger: Phenylacetylenyl phenacyl (PAP) dendron

ORGN 512

Jong I. Lee, jilee@york.cuny.edu, Asnan Riamoni, and Sujit Roy. Department of Chemistry, The City University of New York - York College, 94-20 Guy R. Brewer Blvd., Jamaica, NY 11451
Release of amino acids and carboxylates from the p-hydroxyphenacyl (pHP) derivatives has been reported for biological studies. In the attempt to improve the efficiency of release, to excite the phototriggers with visible light and to capacitate for multiple release; dendron structure is adopted for further derivatization of the pHP phototrigger. Low generation dendron based on phenylacetylenyl phenacyl (PAP) is synthesized to explore photorelease of Tyrosine and phenol. The photolysis of the dendron phototrigger is being investigated.
 

Physical Organic Chemistry, Metal-Mediated Reactions, Asymmetric Reactions and Syntheses
8:00 PM-10:00 PM, Tuesday, August 21, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Organic Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007