Asymmetric nucleophilic additions to carbonyls by organic catalysts

ORGN 581

Xiaojie Lu, brucelu@brandeis.edu, Hongming Li, and Li Deng, deng@brandeis.edu. Department of Chemistry, Brandeis University, 415 South Street, MS015, Waltham, MA 02454
Asymmetric Nucleophilic Additions to Carbonyls constitute one of the most versatile and direct strategy for the generation of chiral alcohols. Using the readily available bifunctional organic catalysts derived from cinchona alkaloids, we have developed a number of highly enantioselective nucleohpilic additions to carbonyls. The strategy of catalyst design, the development of new asymmetric reactions and the applications of such reaction in organic synthesis will be presented in this poster.
 

Physical Organic Chemistry, Metal-Mediated Reactions, Asymmetric Reactions and Syntheses
8:00 PM-10:00 PM, Tuesday, August 21, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Organic Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007