ORGN 159 |
| In order to elucidate biological functions and mechanisms, precise external control over biological processes is necessary. Light represents a superior control element, as it can be easily regulated in timing, location, and amplitude. We are using light-responsive moieties and small organic molecules, in conjunction with biological macromolecules, to create new tools for the light-regulation of gene activity. Specifically, we will report our advances toward the light-regulation of enzymatic activity, protein-protein interaction, and oligonucleotide function. Due to the modularity of our approach, we will be able to quickly advance our in vitro results into bacterial and mammalian cell systems, as well as whole organisms. |
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Total Synthesis, Materials, Devices and Switches, Molecular Recognition and Self-Assembly, Biologically-Related Molecules and Processes
8:00 PM-10:00 PM, Sunday, August 19, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Organic Chemistry |