Chemoenzymatic synthesis of amylose-grafted chitosan and chitin

POLY 476

Yoshiro Kaneko, ykaneko@eng.kagoshima-u.ac.jp, Shun-ichi Matsuda, and Jun-ichi Kadokawa, kadokawa@eng.kagoshima-u.ac.jp. Department of Nano-Structured and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima, 890-0065, Japan
In this study, we synthesized amylose-grafted chitosan and chitin by chemoenzymatic method according to the following reaction manners. First, introduction of maltoheptaose to chitosan was carried out by reductive amination to produce a maltoheptaose-grafted chitosan. This was converted into a maltoheptaose-grafted chitin by N-acetylation. Then a phosphorylase-catalyzed enzymatic polymerization of alpha-D-glucose 1-phosphate was performed from the maltooligosaccharide-chains on those chitosan and chitin derivatives to obtain the amylose-grafted chitosan and chitin, respectively. The products were insoluble in good solvents of individual polysaccharides.
 

Polymers from Renewable Resources
6:00 PM-8:00 PM, Tuesday, August 21, 2007 BCEC -- Exhibit Hall - B2, Poster

Division of Polymer Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007