ORGN 289 |
| Nanopatterning on self-assembled monolayers of molecular receptors (molecular printboards) can be achieved by supramolecular nano-imprint lithography or DPN nanolithography. Using the concept of multivalency, molecules including biomolecules, can be anchored permanently or in a dynamic regime. A second way to pattern surfaces uses dynamic covalent chemistry. This methodology has the same advantages as supramolecular patterning with irreversible confinement, e.g. by reduction of an imine linker. We will discuss the application of patterning surfaces with proteins that selectively recognize cancer cells. In this work we have discovered that under conditions of µCP or DPN lithography covalent reactions are much faster than from solution. |
|
Chemistry of the Mechanical Bond and Beyond
8:00 AM-12:00 PM, Monday, August 20, 2007 BCEC -- 253 A/B/C, Oral
Division of Organic Chemistry |