Size/composition-tunable quantum dots and their bioapplications

ANYL 308

Ming-Yong Han, my-han@imre.a-star.edu.sg, Institute of Materials Research & Engineering, National University of Singapore, 3 Research Link, Singpaore, 117602, Singapore
Colloidal semiconductor nanocrystals (quantum dots) have attracted great attention for their distinguished roles in fundamental studies and technical applications such as biological labeling and optoelectronic devices. In the last two decades, the main efforts have been focused on the preparation of size-tunable binary or core-shell nanocrystals with different emission colors. In our research, we also focus on the development of highly luminescent composition-tunable quantum dots across the whole visible spectrum. The successful preparation of high-quality composition-tunable quantum dots makes the new class of nanomaterials very promising as multicolor biological nanoprobes for imaging, sensing, and drug delivery applications. There is an emphasis on the development of ultrasensitive imaging/spectroscopic detection for multiplexed analysis at cellular or tissue levels. Quantitative multi-parameter analysis of multianalytes is being carried out, which could provide a direct way to identify sets of genes and proteins correlating with certain diseases.