Incorporation and selective localization of bio-nanoparticles in thin film of water-insoluble block copolymer

PMSE 159

Thomas P. Russell, russell@mail.pse.umass.edu1, Dongseok Shin1, Linda K. Molnar2, Seung Hyun Kim3, and Ting Xu4. (1) Department of Polymer Science and Engineering, University of Massachusetts, 120 Governor's Drive, Amherst, MA 01003, (2) Office of the Director, National Cancer Institute, 31 Center Drive, MSC2580, Bethesda, MD 20892, (3) Division of Nano-Systems Engineering, Inha University, Incheon, KOREA, South Korea, (4) Department of Materials Science, University of California Berkeley, Berkeley, CA
A way to incorporate bio-nanoparticles into a thin film of water-insoluble block copolymer has been studied. In this approach, ferritins were adsorbed on films of polystyrene-b-poly(ethylene oxide) and quarternized polystyrene-b-poly(N-methyl-4-vinlpyrdinium iodide) from an aqueous solution and the sample was subsequently annealed under solvent vapor. The humidity of the annealing chamber was critical for the dispersion of bio-nanoparticles and the development of the morphology of the composite. Under high humidity condition, ferritins were dispersed and selectively localized in the microdomains of PEO, while the bio-nanoparticles were aggregated in low humidity case. With PS-b-PQ4VP a co-assembly with the ferritins was observed where the microphase separation of the PS-b-P4VP forced a segregation of the ferritins to the grain boundaries forming a much larger scale structure. Similar results were found with tobacco mosaic virus.
 

Hierarchically Ordered Functional Materials
8:30 AM-12:05 PM, Tuesday, August 21, 2007 Westin Boston Waterfront -- Grand Ballroom E, Oral

Division of Polymeric Materials: Science & Engineering

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007