ORGN 695 |
| Hydrogenation accounts for over half the chiral compounds made by man not produced via physical or enzymatic resolution. This fact portends an equally powerful approach to reductive C-C bond formations mediated by hydrogen – catalytic couplings achieved simply through the exposure of two or more molecules to gaseous hydrogen in the presence of a metallic catalyst. Our laboratory is engaged in the first systematic efforts toward the development of hydrogen-mediated C-C couplings beyond alkene hydroformylation. These transformations add a new dimension to catalytic hydrogenation; one of chemistry's oldest and most broadly utilized processes.
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Modern Organometallic Catalysis
1:00 PM-5:00 PM, Wednesday, August 22, 2007 BCEC -- 253 A/B/C, Oral
Division of Organic Chemistry |
