ORGN 550 |
| The use of preformed sodium carboxylates as substrates led to the first observation of facile Pd-insertions into sp3 ß-C-H bonds in simple aliphatic acids. Consequently, Pd-catalyzed methylation and arylation of o-C-H bonds in benzoic acids and ß-C-H bonds in aliphatic acids using either a phenylboronate, methylboronic acid or ArI have been achieved under basic conditions via a C-H activation/C-C coupling sequence.
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Physical Organic Chemistry, Metal-Mediated Reactions, Asymmetric Reactions and Syntheses
8:00 PM-10:00 PM, Tuesday, August 21, 2007 BCEC -- Exhibit Hall - B2, Poster
Sci-Mix
Division of Organic Chemistry |
