ORGN 66 |
| Carbon nanotubes (CNT) are attracting the attention of several scientists, due to their unique structural, mechanical, electronic, chemical and biological properties. These nanoobjects hold a lot of promises on biomedical applications for different reasons: high stability, water solubility, lack of intrinsic immunogenicity, efficient payload capacity, and rapid cellular uptake. The organic functionalization has facilitated the manipulation of this type of nanomaterial, thus opening the way to the potential use of CNT as a novel vectors for drug delivery. Functionalized CNT can be considered as a promising alternative to the common drug delivery systems. In this context, we have explored the possibility of targeted delivery of small organic molecules (antibiotics and anticancer), peptides and nucleic acids. In this presentation we will describe the functionalization and biological properties of carbon nanotubes loaded with different active cargos. We will also address the critical issue of their toxicity. |
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New Molecular Strategies for Tumor-Targeting Drug Delivery
1:25 PM-5:20 PM, Sunday, August 19, 2007 BCEC -- 253 A/B/C, Oral
Division of Organic Chemistry |