ORGN 547 |
| (E)-1-Alkyl-1-alkenylboronate esters easily prepared by the literature procedures, readily react with trimethylsilylmethyllithium in ether at -78 oC for 2 h. The resulting products are then treated with iodine at -78 oC for 3 h to provide after workup the corresponding (Z)-allylsilanes containing trimethylsilylmethyl moiety in good yields (68%-78%) These (Z)-allylsilanes containing trimethylsilylmethyl moiety are purified by column chromatography over alumina and the structures of these compounds are confirmed by NMR spectral data.
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Physical Organic Chemistry, Metal-Mediated Reactions, Asymmetric Reactions and Syntheses
8:00 PM-10:00 PM, Tuesday, August 21, 2007 BCEC -- Exhibit Hall - B2, Poster
Division of Organic Chemistry |