Asymmetric arylation of α-bromoketones with arylzinc reagents

ORGN 380

Pamela M. Lundin, lundin@mit.edu, Jorge Esquivias, and Gregory C. Fu, gcf@mit.edu. Department of Chemistry, Massachusetts Institute of Technology, Room 18-290, 77 Massachusetts Avenue, Cambridge, MA 02139
A chiral nickel complex allows the catalytic asymmetric cross-coupling of α-bromoketones in high yields and enantioselectivities.

 

Asymmetric Reactions and Syntheses
8:00 AM-12:00 PM, Tuesday, August 21, 2007 BCEC -- 253C, Oral

Division of Organic Chemistry

The 234th ACS National Meeting, Boston, MA, August 19-23, 2007