INOR 503 |
| The development of well defined catalysts with good functional group tolerance has established olefin metathesis as a powerful tool for the formation of carbon-carbon double bonds. Substitution of a phosphine for an N-heterocyclic carbene ligand, in ruthenium-based metathesis catalysts, led to more efficient complexes that maintain the high functional group tolerance and air and moisture stability of the phosphine-containing complexes. Nevertheless, the development of catalysts that could efficiently control E/Z selectivity in cross-metathesis reactions, or afford tetrasubstituted double bond products in ring-closing metathesis reactions, still represents a major challenge. The present work focuses on the synthesis of novel ruthenium-based olefin metathesis catalysts bearing a series of thiazol-2-ylidene ligands. Their structure and catalytic activity in ring-closing metathesis, ring-opening metathesis polymerization, and cross-metathesis reactions will be discussed as well. |
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Organometallic Catalysts
8:30 AM-12:20 PM, Tuesday, August 21, 2007 BCEC -- 211, Oral
Division of Inorganic Chemistry |