Palladium- and nickel-catalyzed coupling reactions

ORGN 692

Gregory C. Fu, Department of Chemistry, MIT, 77 Mass. Ave., Room 18-290, Cambridge, MA 02139
During the past several years, we have pursued the discovery of palladium- and nickel-based catalysts for coupling activated and unactivated primary and secondary alkyl electrophiles that bear β hydrogens. Our recent efforts to develop broadly applicable methods, including enantioselective processes, will be discussed.