COMPTuesday, March 27, 2007

6:00 PM-8:00 PM Sheraton Chicago -- River Exhibit Hall, Poster
General Posters
Organizer:Jeffry D. Madura
A basis set perspective on density functional performance
Brian P. Prascher, Brent Wilson, Angela K. Wilson
Automated pharmacophore query optimization with genetic algorithms: Case study of MC4R
Lei Jia, Jinming Zou, Hongmao Sun
Ab initio calculations on the intramolecular Schmidt reaction
Joseph M. Cannone, Jennifer L. Poutsma
Genetic function approximation insights into Plasmodium falciparum dihydrofolate reductase and farnesyltransferase inhibition
Prasanna Sivaprakasam, Aihua Xie, Perrer N. Tosso, Robert J. Doerksen
Hydrolysis in pure water: Car-Parrinello metadynamics on the hydrolysis of esters at pH7
Hakan Gunaydin, K. N. Houk
Modified effective core potentials for the efficient modeling of metallocenes
John L. Lewin, Christopher J. Cramer
Molecular dynamics simulations of R67 dihydrofolate reductase: Investigation into the cooperative binding
Chuanyin Shi, Jennifer L. Poutsma
On the response of an ionic liquid to external perturbations and the calculation of shear viscosity
Zhonghan Hu, Claudio J. Margulis
Optimization of ROMP poly(norbornene) as a catalyst support using molecular simulations
Andrew T. Swann, Peter J. Ludovice
Prediction of olive oil - water partition coefficients for use in bioavailability models
Adam Chamberlin, Christopher J. Cramer, Donald G. Truhlar
Can we improve hit identification by accounting for conserved water molecules in binding sites?
Michael Brunsteiner, Reaz Uddin, Pavel A. Petukhov
Probing the energetic and structural role of non-covalent interactions in HIV protease
Srinivas Alla, Rajni Garg, Sunil Kumar, Narahari Sastry Garikapati
Paper Withdrawn
Study of structure-activity relationship of steroidal alkaloids analogs as inhibitors of butyrylcholinesterase by 3-D quantitative modeling technique
Reaz Uddin, Zaheer Ul Haq
Comparison of basis set superposition errors for cc-pVnZ and pc-n basis sets
Michael S Marshall, Tracy P. Hamilton
Computational analysis of the role of key residues of formamido-pyrimidine DNA glycosylase in lesion recognition
Kun Song, Carlos De los Santos, Arthur P. Grollman, Carlos Simmerling
Paper Withdrawn
Implementation of non-local electrostatic paradigm opens the door for accurate modeling of electrostatic interactions at the macromolecule-solvent interface
Alexander Rubinstein, Simon Sherman
Orthogonal approach to mass spectral interpretation and library searching
Daniel L. Sweeney
Sub-Kelvin high magnetic field polarization-phase selective electronic structure studies: Challenges for quantum chemistry
Kresimir Rupnik
Computational studies of tertiary structure of lysyl oxidase using the method of dynamic formation and breaking of disulfide bonds
Dr. Faina Ryvkin, John Bluhm
p-p Interactions in heterocyclic molecules
Prantik Kundu, Joseph F. Capitani, Abhijit Mitra, Pamela J. Seaton
Ab initio and DFT benchmark study for nucleophilic substitution at carbon (SN2@C) and silicon (SN2@Si)
A. Patrícia Bento, Miquel Solà, F. Matthias Bickelhaupt
Database docking of protonation/tautomeric forms of selected antagonists with the Alpha-2A adrenergic receptor homology models
Wesley Asher, Kezia Pacheco, Debra Bautista
A new efficient two-electron integration scheme
Yong Feng, Xiaosong Li
Discovery of electronic mechanism of concerted cycloadditions based on quantum chemical calculations
Sengen Sun
Ab initio method for the reactions between hydrogen chloride and protonated ipropyl- and tbuthyl chlorides
Pervin Unal Civcir
Effect of cyanine-3 dye on the stability of oligonucleotide hybrid duplex on microarrays: A molecular dynamics simulation study
Zunliang Wang, Nongyue He
Accelerated minimization of nudged elastic bands for determining minimum energy paths of transitions
Erlendur Jónsson, Hannes Jónsson
Effect of environmental parameters on the chemical signature of TNT in soil, validation of numerical simulations
Maik Irrazabal, Vivian Florian, Miguel E. Castro, Samuel P. Hernandez, Julio Briano
Adsorption of TNT and its degradation products in soil organic matter: Ab initio calculations
Maik Irrazabal, Julio Briano, Arturo Hernandez
Algorithms for fragment based drug discovery
Hugo O. Villar, Jason Hodges, Mark R. Hansen
Alpha2C QSAR studies on a database of ligands optimally protonated for physiological conditions
Kezia Pacheco, Wesley Asher, Debra Bautista
Electronic organizing elements of boron Lewis acid adducts of a,b-enal compounds
Joshua A Plumley, Jeffrey D. Evanseck
An improved REMD sampling method: Temperature intervals with global energy reassignment (TIGER)
Xianfeng Li, Galen Collier, Christopher O'Brien, Feng Wang, Nadeem Vellore, D. A. Bruce, Brian Dominy, Steven J. Stuart, Robert A. Latour Jr.
Analysis of charge distribution in excited states of substituted benzenes
Sheritta Cooks, Tracy P. Hamilton
Estimation of normal frequencies and vibrational entropies from quasi-Newton Hessian optimization
Stanislaw Wlodek, A. Geoffrey Skillman, Anthony Nicholls
Examining the effects of the nucleophile and leaving group in the cleavage of phosphonate ester derivatives
Laura A. Kopff, Erich R. Kuechler, Eric V. Patterson
Aromatic substituent effects on arene-arene binding energies
Shana Beg, Michael Lewis
Atomistic simulation of nanostructure of solvated polymer electrolyte membrane and small molecule transport
Arun Venkatnathan, Ram Devanathan, Michel Dupuis
Automate setup for molecular dynamics simulations of protein/membrane complexes
Ritesh Kumar, Sunhwan Jo, Vidyashankara G Iyer, Wonpil Im
Calculations on hexafluorocyclopropane and its “bond-stretched invertomer”
Haiyan Wei, David A. Hrovat, Weston Thatcher Borden
Fragment linking using molecular shape
Geoffrey Skillman, Anthony Nicholls
CHARMM-GUI: A graphical user interface for the CHARMM users
Ritesh Kumar, Vidyashankara G Iyer, Wonpil Im
Cheminformatics: Chelation vs. toxicity
Adam C. Lee, Gordon M. Crippen
Comparing field-based and atom type-based electrostatic similarity
Robert Tolbert, Geoffrey Skillman, Paul Hawkins, Anthony Nicholls
Mechanism of the Schmidt reaction
Donna G. English, Jennifer L. Poutsma
Computational approach for predicting biodegradation rates of alkylnaphthalenes
Vito Librando, Andrea Alparone
Computational modeling and Brownian dynamics simulation of C. reinhardtii hydrogenase - ferredoxin docking complexes
Hai Long, Christopher H. Chang, Paul King, Maria L. Ghirardi, Kwiseon Kim
Computational studies of metalloporphyrin-oxygen systems
Jillian Lennartz, John Morrison Galbraith
Computational studies on RPE65
Hao Guo, Chong Zheng, Elizabeth R Gaillard
Effects of binding and wave diffusion during controlled rate drug delivery
Kal Renganathan Sharma
On the separation of styrene from ethylbenzene using a Z step-wise cross-current extraction procedure
Kal Renganathan Sharma
Computational studies on the nucleophilic destruction of nerve agent VX
Kelly A Daniel, Laura A. Kopff, Eric V. Patterson
Computational study of IdeS inhibitors
Robert A. Grimminger, Jeffrey P. Wolbach
Computer modeling study of small molecular inhibitors of ubiquitin-activating enzyme (E1)
Zengjian Hu, Yili Yang, William M. Southerland
Performance of density functional theory for transition metal-containing complexes using correlation consistent basis sets
Sammer M. Tekarli, Thomas R. Cundari, Angela K. Wilson
R67 Dihydrofolate Reductase: Full ligand binding modes and effects on binding cooperativity
Jessica L. Bass, Jennifer L. Poutsma
Computer simulation of Escherichia coli peptide déformylase
Abdelouahab Chikhi
Conformational interconversion mechanisms of tetraoxacyclohexanes (Tetraoxanes): A theoretical study
Fillmore Freeman, Chansa Cha, Elika Derek, Chinh Do, Jung H. Hwang, Lisa Phung, Quyen T. Phung, Travis Picorelli, Tina Wang
Density functional computations of substituent effects on energetics of ethylene polymerization mediated by zirconocene catalysts
Paritosh Das, Don C. Becker, Danny G. McGuire
Relative stability of intermediates in the lipid peroxidation of arachidonic acid
Claire E. Tornow, M. C. Milletti
Development of docking protocols and scoring functions using frequent geometric and chemical patterns of inter-atomic interactions at the interface of protein-ligand complexes
Raed Khashan, Weifan Zheng, Alexander Tropsha
Effect of modifications on the dihedral angles of peptide nucleic acids
Anna K. Manukyan, Jennifer Radkiewicz-Poutsma
Electron attachment to the microsolvated Watson-Crick guanine cytosine base pair
Jun D. Zhang, Henry F. Schaefer III
Estimation of vitamin-D receptor ligand binding affinity using a new multistep computer-aided approach
Sivanesan Dakshanamurthy, Md. Naimul Islam, Salimmudin Shah, Stephen Byers
Evaluation of descriptors that discriminate between CYP metabolized substrates
John H. Block, Douglas Henry
Exploring folding landscapes with a flavored Go model
Ronald D. Hills Jr., Sagar Kathuria, Robert C. Matthews, Charles L. Brooks III
Tautomerization mechanisms in 2-pyrimidinethiols: A theoretical study
Fillmore Freeman, Henry N. Po
Factors that shift Lewis acid catalyzed aza-Diels-Alder reactions to a stepwise mechanism
Anthony J. Ross, Jeffrey D. Evanseck
Valence bond interpretation of 4 electron, 3 center g systems
Andrew DeBlase, John Morrison Galbraith
FLIPDock: Docking flexible ligands into flexible receptors
Yong Zhao, Michel F. Sanner
High-speed pseudo-orthogonalization for the Car-Parrinello method
Umpei Nagashima, Tomoo Aoyama
Implemention of the fast multipole method in molecular dynamics
Reid G. Ormseth, R. Pachter
Implicit solvation modeling drug permeability of Caco-2 membranes
Natalie Elmasry, Casey P. Kelly, Christopher J. Cramer, Donald G. Truhlar
Improvement of nonbonded QM/MM interaction energies
Timothy J. Giese, Darrin M. York
Inhibitors of pantothenate synthetase: Initiating a quest for new tuberculosis drugs
Pavel A. Petukhov, Michael Brunsteiner, Reaz Uddin
Intersystem crossing dynamics in acetylene
Bryan M. Wong, Ryan L. Thom, Robert W. Field
Investigating M20 loop conformers of dihydrofolate reductase
Jennifer Poutsma, Jeffrey A. Tibbitt
Paper Withdrawn
Kinetic isotope effects and free energy barriers of methyl triphosphate hydrolysis
Yun Liu, Darrin M. York
Modeling of human glutathione synthetase: An ATP-Grasp enzyme
Mary E. Anderson, Thomas R. Cundari, Adriana Dinescu, Monique Carter, Sara Hernandez
Molecular dynamics simulations of oligonucleotide hybrid duplexes containing different length of polythymidine spacer sequence with one end tethered: Free energy comparison and stability analysis
Zunliang Wang, Song Li, Nongyue He
Molecular dynamics study of inhibitor binding to bacterial ribosome
Xiaoxia Ge, Benoit Roux
Molecular orbital of fragment molecular orbital method with Sakurai-Sugiura method on grid computing environment
Umpei Nagashima, Toshio Watanabe, Yuichi Inadomi, Hiroaki Umeda, Takayoshi Ishimoto, Tetsuya Sakurai
MRPT investigations of the ground state of NiO2
Jie Song, George Schoendorff, Yury G. Khait, Mark R. Hoffmann
Olefin coordination effects upon aza-bis(oxazoline) copper(I) catalyzed cyclopropanation
Lauren M. Matosziuk, Jeffrey D. Evanseck
P450 inhibition: Some insights from data mining, docking and crystal structural studies
Hongwu Wang, Peter Orth
Predicting and validating the binding site of telmisartan: Molecular dynamics simulation of the G-protein-coupled angiotensin II receptor
Akshay Patny, Prashant V. Desai, Mitchell A. Avery
Pressure annealing as a complement to simulated annealing for conformational sampling of long-chain oligomers
Ralph A. Wheeler, Christopher Adam Hixson
Protein interaction score (PI-Score): The derivation and validation of a novel empirical free energy function that explains and predicts protein-protein binding affinities
Joseph Audie
PI-Score and accurate protonation state assignment can be used to rationalize the binding thermodynamics of the OppA peptide binding protein
Joseph Audie, Craig Bleaken, May May Cheng
Secondary structure bias in generalized Born solvent models: Comparison of conformational ensembles and free energy of solvent polarization from explicit and implicit solvation
Daniel R. Roe, Viktor Hornak, Carlos L. Simmerling
Side-chain and backbone ordering in homopolymers
Yanjie Wei, Walter Nadler, Ulrich HE. Hansmann
Stability and structure of oligomers of the Alzheimer peptide from computer simulations
Jie Zheng, Buyong Ma, Hyunbum Jang, Ruth Nussinov
Steered molecular dynamics (SMD) simulation of anthrax edema factor translocation through a protective antigen pore
Michael R Lacina, Anne Loccisano, Jeffrey D. Evanseck
Stereoelectronic effects in phosphates
Eliza A. Ruben, Jeffrey D. Evanseck, Michael S. Chapman
Structure determination of water clusters of serotonin and its protonated form using computational method
Young S. Lee, Hyo Jin Lee, Sungwoo Jang, Seung Hyun Lee, Sung Il Jin, Ji Yeon Lee, C. R. Park
Substrate binding and kinetic aspects of the oxygenation reaction mechanism in COX-1
Mark A Lukowski, M. C. Milletti
The structural origin of melting temperatures in DNA dumbbell conjugates as determined by molecular dynamics
Martin McCullagh, George C. Schatz, Frederick D. Lewis
The structure and organization of fatty alcohols at the water/vapor interface: A molecular dynamics study
Tsun-Mei Chang, Michelle M. Dolnik
The theory study on the absorption chromatograph of Cd(II) complex with 2,2'-bipyridine and terephthalate
Lihua Chen
Using ensembles of protein conformations in structure-based drug discovery
Kelly L. Damm, Kristin L. Meagher, Heather A Carlson

Symposium Grid -- Division of Computers in Chemistry -- Session Listing

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007