MEDISunday, March 25, 2007

1:30 PM-5:30 PM McCormick Place Lakeside -- Room E353 A/B, Level 3, Oral
First Time Disclosure of Clinical Candidates
Organizer, Presiding:Andrew W. Stamford
1:30 PMIdentification of GSK625433: A novel clinical candidate for the treatment of hepatitis C
David Haigh, Elizabeth M. Amphlett, Gianpaolo S. Bravi, Helen Bright, Victoria Chung, C. Lynn Chambers, Anne G. Cheasty, Maire A. Convery, Malcolm R. Ellis, Rebecca Fenwick, D. Fraser Gray, C. David Hartley, Peter D. Howes, Richard L. Jarvest, Katrina J. Medhurst, Abdul Mehbob, Debbie Mesogiti, Fereshteh Mirzai, Fabrizio Nerozzi, Nigel R. Parry, Neil Roughley, Tadeusz Skarzynski, Martin J. Slater, Stephen A. Smith, Richard Stocker, Colin J. Theobald, Pamela J. Thomas, Pia A. Thommes, James H. Thorpe, Claire S. Wilkinson, Emily Williams
2:10 PMIdentification and development of inhibitors of PI3K and related protein kinases for cancer treatment
Michel Maira, Frederic Stauffer, Pascal Furet, Hans-Georg Capraro, Philipp Holzer, Carlos Garcia-Echeverria
2:50 PMPreclinical antitumor activity of BMS-690514, a panHER/VEGFR2 kinase inhibitor
Ashvinikumar V. Gavai, Ping Chen, Derek Norris, Brian E. Fink, Harold Mastalerz, Yufen Zhao, Wen-Ching Han, Guifen Zhang, Walter Johnson, Edward Ruediger, Pierre Dextraze, Jean-Paul Daris, Soong-Hoon Kim, Kenneth Leavitt, Kyoung Kim, Songfeng Lu, Peter Zheng, Arvind Mathur, Dinesh Vyas, John S. Tokarski, Chiang Yu, Simone Oppenheimer, Hongjian Zhang, Francis Lee, Tai W. Wong, Gregory D. Vite
3:30 PMThe discovery of MK-0812, a potent and selective CCR2 antagonist
Lihu Yang, Richard X. Jiao, Chris Moyes, Greg Morriello, Gabor Butora, K. Shankaran, Alexander Pasternak, Steve Goble, Changyou Zhou, Malcolm MacCoss, Anne-Marie Cumiskey, Larry Peterson, Mike Forrest, Julia M. Ayala, Hong Jin, Julie DeMartino, Sander G. Mills
4:10 PMDiscovery of PF-184298, a dual serotonin/noradrenaline reuptake inhibitor
Gavin A. Whitlock, Florian Wakenhut, Alan Stobie, Paul V. Fish, M. Jonathan Fray
4:50 PMDiscovery of MK-0974: A potent, orally bioavailable calcitonin gene-related peptide (CGRP) receptor antagonist for the treatment of migraine
Daniel V. Paone, Anthony Shaw, Diem Nguyen, Chris Burgey, James Deng, Craig Stump, Amy Quigley, Jane DeSolms, Stefanie Kane, Ken Koblan, Rodney Bednar, John Mallee, Scott Mosser, Chris Salvatore, Daniel McMasters, Jim Hershey, Halea Corcoran, Betsy Lyle, Brad Wong, Shane Roller, Cindy Miller-Stein, Janice Rowe, Sean Yu, Sam Graham, Joseph Vacca, Theresa Williams

Symposium Grid -- Division of Medicinal Chemistry -- Session Listing

Symposium Grid -- Biotechnology -- Session Listing

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007