INOR 878 |
| Biodegradable polymers are used in a wide variety of biomedical applications, which include the controlled release of therapeutic drugs and medical devices such as stents. Ring-opening polymerization (ROP) of cyclic esters produces polyesters, which are a major class of biodegradable polymers. We are interested in using molecular architectures that allow a specific approach of the substrate to the metal center. One of our targets is the use of lanthanide centers supported by rigid macrocycles, which allow axial access of the incoming substrate, as general catalyst systems to generate new biodegradable copolymers. Our attempts to synthesize and characterize alkoxide lanthanide complexes (Ln = Gd, Y) and preliminary studies on their catalytic behavior in the ROP of cyclic esters will be reported. |
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Chemistry of Lanthanide and Actinide Systems
7:00 PM-10:00 PM, Tuesday, March 27, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Sci-Mix
Division of Inorganic Chemistry |