eHiTS and the Sun Grid Compute Utility: Using massively parallel computation for docking

COMP 300

Darryl Reid1, Aniko Simon1, Zsolt Zsoldos1, Bashir Sadjad, bashir@simbiosys.ca1, Marty Duey, Marty.Duey@sun.com2, and Brian Foley, Brian.Foley@sun.com2. (1) SimBioSys Inc, 135 Queen's Plate Dr, Suite 520, Toronto, ON M9W 6V1, Canada, (2) Sun Microsystems Inc, 4150 Network Circle, Santa Clara, 95054
The parallel nature of virtual ligand screening makes it ideal for distributed computing architectures, such as the Sun Grid Compute Utility (SGCU). The SGCU provides easy and affordable access to an enormous computing resource. The eHiTS docking tool is one of the first applications to be deployed on the SGCU and has shown superb scalability. eHiTS is one of the easiest to use and most accurate docking programs available and it is ideally suited for the SGCU environment. Details of how medium to large scale screens can be ran in a shortened period of time will be discussed. eHiTS on the SGCU is a great choice for those with limited internal compute power, or those that need supplemental CPU cycles for a short period of time. for eHiTS see: http://www.simbiosys.ca/ for SGCU see: http://www.network.com/
 

General Oral: Drug Discovery
1:30 PM-6:30 PM, Thursday, March 29, 2007 McCormick Place North -- Room N136, Level 1, Oral

Division of Computers in Chemistry

The 233rd ACS National Meeting, Chicago, IL, March 25-29, 2007