CHED 579 |
| A family of alkoxyalkenes 4 has been formed through a quick procedure. The novel alkyne 3 can be conveniently made in good yield. The solvent used in the chlorination of propiolic acid 1 is critical. There has been no problems with sterics or any problem preventing the type of alcohol being added to the alkyne 3 to make the final products 4. E/Z ratios are high, and E/Z isomers of 4 are easily separable. For the ester analogs the E/Z ratios are mediocre and isomers are not easily separable. Products 4 and related substrates are being investigated for their reactivity towards Grignard reagents, Diels-Alder reactions, and Pauson-Kahn cyclization reactions.
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Undergraduate Research Poster Session: Organic Chemistry
11:00 AM-1:00 PM, Monday, March 26, 2007 Hyatt Regency Chicago -- Riverside Center, Poster
Division of Chemical Education |
